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Pathology Outlines - GATA3

Oct 14, 2020  · Pathology Outlines - GATA3. Stains & molecular markers. GATA3. Author: Emily S. Reisenbichler, M.D. Editorial Board Member: Maria Tretiakova, M.D., Ph.D. Deputy Editor-in-Chief: Debra L. Zynger, M.D. Topic Comple...

https://www.pathologyoutlines.com/to... 

GATA3: a multispecific but potentially useful marker in ...

GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors. GATA3 is a transcription factor important in the differentiation of breast epithelia, urothelia, and sub...

https://pubmed.ncbi.nlm.nih.gov/2414... 

GATA3 - Libre Pathology

GATA3 an immunostain that is increasingly used in genitourinary pathology.

https://librepathology.org/wiki/GATA... 

GATA3 expression in small cell carcinoma of bladder and ...

Nuclear GATA3 expression was encountered in 7 bladder (7/22, 32%) and 2 lung (2/15, 13%) small cell carcinomas. All 33 primary prostate small cell carcinomas were negative. Among bladder tumors, strong and diffuse (>75%) GATA3 labeling was seen...

https://pubmed.ncbi.nlm.nih.gov/2492... 

GATA3 Immunohistochemistry for Distinguishing Sarcomatoid ...

GATA binding protein 3 (GATA3) is most commonly used as an immunohistochemical marker of breast and urothelial carcinoma, but is also known to stain other types of tumors including some mesotheliomas.

https://pubmed.ncbi.nlm.nih.gov/2861... 

Usefulness of GATA3 and p40 Immunostains in the Diagnosis of Metast…

Usefulness of GATA3 and p40 Immunostains in the Diagnosis of Metast…

https://acsjournals.onlinelibrary.wi... 

Usefulness of GATA3 and p40 Immunostains in the Diagnosis of Metast…

Usefulness of GATA3 and p40 Immunostains in the Diagnosis of Metast…

https://acsjournals.onlinelibrary.wi... 

Immunohistochemical Evaluation of GATA3 Expression in ...

Immunohistochemical Evaluation of GATA3 Expression in ...

https://academic.oup.com/ajcp/articl... 

GATA3 Expression in Common Gynecologic Carcinomas: A Potential Pitf…

GATA3 Expression in Common Gynecologic Carcinomas: A Potential Pitf…

https://pubmed.ncbi.nlm.nih.gov/3005... 

GATA3 Expression in Common Gynecologic Carcinomas: A ...

GATA binding protein 3 (GATA3) immunohistochemistry is primarily used as a marker of breast and urothelial differentiation, particularly in metastatic settings. In the gynecologic tract it also serves a robust marker for mesonephric and trophoblas...

https://pubmed.ncbi.nlm.nih.gov/3005... 

Utility of GATA3 in the differential diagnosis of ...

Aims: GATA3 is a relatively new immunohistochemical marker which shows consistent nuclear expression in a variety of tumours, including breast and urothelial carcinoma. The staining pattern of GATA3 in adrenal lesions is not well established.

https://pubmed.ncbi.nlm.nih.gov/2837... 

Pathology Outlines - Invasive urothelial carcinoma

Apr 06, 2021  · 8120/3 - infiltrating urothelial carcinoma. 8131/3 - micropapillary urothelial carcinoma. 8082/3 - lymphoepithelioma-like urothelial carcinoma. 8122/3 - sarcomatoid urothelial carcinoma. 8031/3 - giant cell urothelia...

https://www.pathologyoutlines.com/to... 

Pathology Outlines - Mycosis fungoides

Apr 15, 2021  · Sample pathology report. Skin, left flank, punch biopsy: Epidermotropic T-cell infiltrate, suspicious for mycosis fungoides (see comment) Comment: This lesion has Pautrier-type microabscesses comprised of CD4+ T-cell...

https://www.pathologyoutlines.com/to... 

Pathology Outlines - PathologyOutlines.com

PathologyOutlines.com, free, updated outline surgical pathology clinical pathology pathologist jobs, conferences, fellowships, books

https://www.pathologyoutlines.com/ 

GATA3 - Wikipedia

The GATA3 gene is located close to the end of the short arm of chromosome 10 at position p14. It consists of 8 exons, and codes for two variants viz., GATA3, variant 1, and GATA3, variant 2.

https://en.wikipedia.org/wiki/GATA3 

Immunohistochemical profiles in primary lung cancers and ...

Primary lung squamous cell carcinomas expressed CK5, p40, and p63 in 94%-97% of cases, whereas 44% were positive for CK7, 20% for GATA3, 7% for CDX2, and 3% for TTF-1. Rare cases expressed PAX8, CK20, or napsin A. Pulmonary metastases of colorecta...

https://pubmed.ncbi.nlm.nih.gov/3038... 

Printable - Prostatic Adenocarcinoma - Surgical Pathology ...

Feb 02, 2016  · GATA3 is sensitive (90%) and specific (also reacts with TCC) ... Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. IARC Press. Lyon 2004. Kaleem Z, Swanson PE, Vollmer RT, Humphrey PA. ...

http://surgpathcriteria.stanford.edu... 

Printable - Nephrogenic Adenoma - Surgical Pathology ...

Most lesions have both a surface papillary and a submucosal tubular componentPapillae and tubules are both lined by a single layer of bland cells with pale to clear cytoplasmLining cells are typically bland, mitotically inactiveFrequently associa...

http://surgpathcriteria.stanford.edu... 

Semiquantitative GATA-3 Immunoreactivity in Breast ...

Jan 07, 2014  · GATA-3 expression was evaluated by immunohistochemistry in 198 invasive breast carcinomas on tissue microarrays. Tissue microarrays of other tissues included 144 gynecologic tumors, 28 bladder carcinomas, 63 cholangi...

https://academic.oup.com/ajcp/articl... 

Pathology Outlines - Cytokeratin AE1 / AE3

Stains - Cytokeratin AE1 / AE3: keratin cocktail that detects CK1 - 8, 10, 14 - 16 and 19, but does not detect CK17 or CK18

https://www.pathologyoutlines.com/to... 

GATA3: A Multispecific But Potentially Useful Marker in ...

GATA3 has been thus far explored in surgical pathology as a marker for breast and urothelial carcinomas [13] and is frequently used to discriminate between primary or metastatic mammary and ...

https://www.researchgate.net/publica... 

Usefulness of GATA3 and p40 Immunostains in the Diagnosis ...

BACKGROUND: GATA3 (GATA-binding protein 3) expression in urothelial carcinoma (UC) and mammary carcinomas has been recently reported. However, to the authors’ knowledge, studies examining GATA3 staining of metastatic UC (MUC)

https://acsjournals.onlinelibrary.wi... 

GATA3 is a sensitive marker for ... - Diagnostic Pathology

Jul 10, 2017  · GATA-binding protein 3 (GATA3) has been identified as a sensitive marker for breast carcinoma but its sensitivity in primary genital extramammary Paget diseases (EMPDs) has not been well studied. Here we investigated...

https://diagnosticpathology.biomedce... 

GATA3 - Humpath.com - Human pathology

PO. Definition: GATA3 is a zinc-finger transcription factor (ZFNs), which is expressed in various normal and neoplastic tissues.. GATA3 is a transcription factor important in the differentiation of breast epithelia, urothelia, and subsets of T-lym...

https://humpath.com/spip.php?article... 

GATA3 and APOBEC3B are prognostic markers in ...

GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma and APOBEC3B is directly transcriptionally regulated by GATA3.

https://pubmed.ncbi.nlm.nih.gov/3293... 

The utility of CDX2, GATA3, and DOG1 in the diagnosis of ...

GATA3 was positive in all choriocarcinomas (sensitivity, 100%). Weak GATA3 immunostaining was also seen in 12% of yolk sac tumors and 2 of 2 primitive neuroectodermal tumors. DOG1 was negative in all tumors, but stained spermatocytes and spermatid...

https://www.sciencedirect.com/scienc... 

Role of GATA3, CK7, CK20 and CK14 in distinguishing ...

GATA3-binding protein 3 (GATA3) is a novel immunohistochemical marker for UC; however, few studies have investigated the role of GATA3 as a marker for urinary bladder SCC.

https://www.researchgate.net/publica... 

Prognostic impact of GATA binding protein-3 expression in ...

May 01, 2017  · GATA binding protein-3 (GATA3) is a transcription factor that regulates cell differentiation and maintenance in some types of normal cells. This study aimed to investigate the association between GATA3 expression and...

https://www.sciencedirect.com/scienc... 

Immunohistochemical Evaluation of GATA3 Expression in ...

Jan 07, 2012  · GATA3 (GATA binding protein 3 to DNA sequence [A/T]GATA[A/G]) is 1 of 6 members of a zinc finger transcription factor family, and it plays an important role in promoting and directing cell proliferation, development,...

https://academic.oup.com/ajcp/articl... 

Pathology Outlines - Board Review Style Questions

GATA3. This is intrathyroidal parathyroid adenoma. Comment Here Reference: Atypia of Undetermined Significance / Follicular Lesion of Undetermined Significance (AUS / FLUS)

https://www.pathologyoutlines.com/re... 

P40 - Libre Pathology

"Usefulness of GATA3 and p40 immunostains in the diagnosis of metastatic urothelial carcinoma in cytology specimens.". Cancer Cytopathol 122 (6): 468-73. doi : 10.1002/cncy.21424 .

https://librepathology.org/wiki/P40 

Pathology Outlines - with GATA2 mutation

Mar 29, 2021  · 16 year old boy with acute myeloid leukemia and severe bilateral warts on hands and fingers since childhood (Leuk Lymphoma 2020;61:3010) 22 year old woman with acute monoblastic leukemia diagnosed at age of 13 (Br J ...

https://www.pathologyoutlines.com/to... 

Aberrant Gata-3 Expression in Human Pancreatic Cancer ...

[392] [393][394] GATA3 forms a complex with LMO2, and TAL1 is aberrantly expressed in T-ALL. 395 Th e direct evidence for the role of GATA3 in T-ALL came from the fi nding that enforced GATA3 ...

https://www.researchgate.net/publica... 

Prognostic impact of GATA binding protein-3 expression in ...

GATA binding protein-3 (GATA3) is a transcription factor that regulates cell differentiation and maintenance in some types of normal cells. This study aimed to investigate the association between GATA3 expression and primary lung adenocarcinoma an...

https://www.sciencedirect.com/scienc... 

Immunohistochemical Distinction of Primary Sweat Gland ...

Morphologic mimicry between two clinicopathologic entities can produce substantial diagnostic challenges. Indeed, that fact largely accounts for the important role that immunohistochemistry (IHC) currently plays in diagnostic anatomic pathology. O...

https://academic.oup.com/ajcp/articl... 

pathology – Page 2 – Blog | PathologyOutlines.com

Feb 16, 2021  · Posts about pathology written by pathologyoutlinesblog. Type your email in the box and click "Follow" to follow our blog.

https://pathologyoutlinesblog.wordpr... 

GATA3 Expression in Common Gynecologic Carcinomas: A ...

ribed in more common malignancies of gynecologic tract including ovarian, endometrial, and cervical carcinomas. Data on the distribution of GATA3 expression in gynecologic malignancies is somewhat limited, particularly across different histologic ...

https://journals.lww.com/intjgynpath... 

Tissue expression of GATA3 - Staining in seminal vesicle ...

gata3. summary. tissue. cell type. pathology. brain. blood. cell. tissue atlas primary data seminal vesicle. adipose tissue adrenal gland amygdala appendix b-cells basal ganglia bone marrow breast bronchus cerebellum cerebral cortex cervix, uterin...

https://www.proteinatlas.org/ENSG000... 

Differential Expression Patterns of GATA3 in Uterine ...

Author information: (1)Department of Anatomic Pathology, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio. GATA binding protein 3 (GATA3) is a recently de...

https://www.ncbi.nlm.nih.gov/pubmed/... 

Utility and pitfalls of GATA3 immunocytochemistry for ...

Mar 01, 2017  · Materials and methods We retrospectively searched our institution's pathology database for cytologic cases where GATA3 immunostaining was performed during diagnostic workup and identified a total of 178 cases, consis...

https://mdanderson.elsevierpure.com/... 

Aggressive Metastatic GATA3-Positive Sarcomatoid Carcinoma ...

Objective . GATA3-positive sarcomatoid carcinoma has never been documented in the past. It is a case of aggressive tumor, positive for GATA3, which should be further studied for its prognostic and therapeutic significance.

https://www.hindawi.com/journals/cri... 

(PDF) GATA3: a multispecific but potentially useful marker ...

G ATA3-binding protein, commonly and from here on abbreviated as GATA3, is a transcription factor of the GATA family. These nuclear proteins recognize G-A-T-A nucleotide sequences in target gene promoters and activate or repress those genes. 1,2 G...

https://www.academia.edu/7641188/GAT... 

Differential expression of GATA-3 in urothelial carcinoma ...

Jul 01, 2014  · GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors Am J Surg Pathol , 38 ( 2014 ) , pp. 13 - 22 View Record in Scopus Google ...

https://www.sciencedirect.com/scienc... 

Nephrogenic Adenoma - PathoBasic

GATA3, p63, CK20) DD Prostatic Adenocarcinoma •More homogenous glands •Cystic and atrophic patterns uncommon •When involving urinary bladder high Gleason grade •Solid ore cribriform architecture common •Pax-2 or Pax-8 negative •Elevate...

https://pathobasic.files.wordpress.c... 

Expression of GATA3 in cancer - Summary - The Human ...

Expression of GATA3 (HDR) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.

http://www.proteinatlas.org/ENSG0000... 

Utility and pitfalls of GATA3 immunocytochemistry for ...

Mar 01, 2017  · Introduction. Although GATA3 expression has been studied extensively on histology specimens and has demonstrated a high level of accuracy in detecting carcinomas from breast or urothelial origin, its utility on cytol...

https://www.sciencedirect.com/scienc... 

mesothelioma search google: mesothelioma gata

Sep 29, 2018  · mesothelioma search google: mesothelioma gata ... mesothelioma

https://mesomesotheliomainfo.blogspo... 

9 February 2021: Image Quiz #49 – Blog | PathologyOutlines.com

Feb 09, 2021  · Posted on February 9, 2021 December 17, 2020 Author pathologyoutlinesblog Categories Image Quiz Tags cervical neoplasm, Cervix, Image Quiz, micro images, pathology, Pathology Outlines, pathologyoutlines, pathologyout...

https://pathologyoutlinesblog.wordpr... 

CK20 and CK5/6 Immunohistochemical Staining of Urothelial ...

Cytokeratins belong to the family of intermediate filaments. They are expressed in a highly specific manner in epithelial cells where they play a crucial role in the integrity and mechanical stability of the cells. Several types of cytokeratins ha...

https://www.hindawi.com/journals/au/... 

Immunohistochemistry and Bladder Tumours

GATA3 *Nuclear transcrip on factor *Iden fied through cDNA microarray studies (2007) *67-90% of urothelial carcinomas *It also stains lymphocytes *It also stains other tumours: Ø breast (ductal and lobular carcinoma) Ø paraganglioma ...

http://www.cpd.utoronto.ca/pathology... 

Urachal cyst pathology | DermNet NZ

Failure of complete urachal lumen closure causes urachal cysts or a free communication between the bladder and the urachus in which urine leaks from the umbilicus.. Histology of urachal cyst. These are lined by urothelium, cuboidal, flat or atroph...

https://www.dermnetnz.org/topics/ura... 

Application of Immunohistochemistry in Breast Pathology: A ...

The World Health Organization's Pathology and Genetics of Tumours of the Breast and Female Genital Organs states “invasive breast carcinoma is a group of malignant epithelial tumours characterized by invasion of adjacent tissues and a marked ten...

https://meridian.allenpress.com/aplm... 

Value of GATA3 Immunostaining in the Diagnosis of ...

mical marker for parathyroid differentiation in tumors. Immunoreactivity for GATA3 was nuclear and was demonstrated in all 10 hyperplastic parathyroid glands, 22 parathyroid adenomas, and 6 parathyroid carcinomas; whereas, all thyroid tumors, rena...

https://journals.lww.com/appliedimmu... 

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